inconvenience
Definitions
A state or instance of trouble, difficulty, or discomfort.
Something that causes annoyance or minor disruption to one's plans or comfort.
Examples
I apologize for any inconvenience this delay may have caused you.
The construction work on the main road is a major inconvenience for local commuters.
Please let us know if the scheduled meeting time causes you any inconvenience.
Synonyms
nuisance bother trouble annoyance hindrance difficulty hassle