invalidate
Definitions
To weaken or destroy the cogency or effectiveness of an argument, theory, or claim.
To deprive of legal force or official validity; to nullify.
To render something ineffective or incapable of functioning correctly.
Examples
The discovery of new evidence will likely invalidate the previous scientific theory.
Failure to sign the document will invalidate your application for the scholarship.
The referee's decision to award a penalty did not invalidate the team's hard-earned victory.