significant
Definitions
Sufficiently great or important to be worthy of attention; noteworthy.
Having a particular meaning; indicative of something.
Statistically likely to be caused by something other than mere chance.
Examples
The research team made a significant breakthrough in the treatment of the disease.
There has been a significant increase in the number of people working from home this year.
The new policy will have a significant impact on the company's long-term growth.
Synonyms
important meaningful substantial notable consequential momentous considerable
Antonyms
insignificant trivial unimportant negligible minor inconsequential meaningless